Monday, May 16, 2016

Chronic Obstructive Respiratory Disease: COPD

Chronic Obstructive Respiratory Disease:
COPD is known to be a progressive respiratory disease that makes it harder to breathe over time. Since COPD is a collection of conditions such as emphysema as well as chronic obstructive bronchitis, usually characterized with persistent airflow limitation, which is not reversable by broncho-dilators. One suggestion is that cigarette smoking predisposes to bacterial colonization and that bacterial products then contribute to inflammation, activation of proteases, and alteration in subsequent host responses to inhaled toxicants. (C)

The relationships between mucous hyper-secretion, pathogenetic mechanisms of emphysema, and airways obstruction are to this day not well understood. Early epidemiological studies of occupational cohorts have failed to associate mucous hyper-secretion with the rapid progression of COPD. The term COPD actually includes 2 different respiratory conditions: Chronic Bronchitis and Emphysema.
 
Chronic Bronchitis:
This is a long term condition of COPD, where the airways swell so much so that they cause phlegmy cough and wheezing, making it hard to breathe. This inflammation of the airways which causes these coughs and production of mucus lasts for most days for several months within the time span of two years occurring in a row. Mucous Hypersecretion is often induced by inflammation where the substantial gland enlargement does not occur.

Bronchitis is related to the hyperplasia of epithelial goblet cells and submucosal glands that are located in the airways. Many of the cellular pathways which vary in different forms of stimuli such as reactive oxygen species, increase of epithelial mucin secretion still need to be identified. There is even more ambiguity of how submucosal glands are regulated. (C)
 
Emphysema:
Emphysema occurs when there is damage to the air sacs in the lungs, where individuals experience shortness of breath and a tight feeling in the chest. Emphysema condition of COPD is a disease that damages the air sacs and may damage the small airways in the lungs. (A)

To reverse emphysema, researchers have to find a way to accomplish this by increasing the number of alveoli. During late fetal and postnatal development, the seperation of the alveoli occurs. Often times it is assumed that the lungs of an adult lack any alveolar plasticity if the emphysema is caused by 'elastase' in adult rats that reversed by treatment of all trans retinoic acid.

Currently, studies are being performed to identify the chemical markers of COPD. Subjects with stable COPD had elevated markers of oxidative stress in exhaled air. of inflammation in serum and sputum, and elastin degradation in urine. The results suggest that multifaceted characterization of COPD patients may be possible by noninvasive means.(C)
 Diagnosis:
Individuals who experience wheezing, coughing, tightening of the chest, and shortness of breath for long periods of time where breathing becomes progressively difficult it is quiet possible that they are suffering from Chronic Lower Respiratory Disease or COPD. Symptoms usually vary on a daily basis. To determine whether a patient has COPD, the physician performs a test called 'spiro-metry'. This measures how much air the lungs can hold and how much force is needed to breathe out. (D)

Diagnosis of COPD during its later stages is very dangerous because the disease has progressed so much so that it has already caused such severe damage that it cannot be reversed. The slow progression of COPD comes with acute exacerbation with increased dyspnea, and mucous production. (Many times the cause of exacerbation, role of pathogens, and acute exacerbations as well as their influence in the progression of COPD are still ambigious and unknown. There needs to be more research in COPD and how to reverse these damages.)

Often times it is difficult to be able to recognize the varying symptoms between COPD and asthma. Not only is COPD a more severe disease than asthma, but inflammatory cells and cytokines (found in allergy diseases) are elevated in patients' COPD's airways. Patients with COPD tend to show considerable, albeit partial, reversal of airflow limitation with bronchodilators. A hallmark characteristic of asthema is methacholine reactivity which is associated with deceleration of FEV1 in patients with COPD. However, there have been observations from studies and research where transgenic mice are over expressing mediators related to asthma and allergy diseases that have shown airway neutrophilia and emphysema (common characteristics of COPD). (C)
Treatment:
Although COPD is a serious and progressive disease, there are medicines available—including bronchodilators—that may help manage its symptoms. Bronchodilators are a type of medicine that help open the airways to make it easier to breathe. Beta-agonists are a type of bronchodilator that work by relaxing tightened muscles around the airways. Beta-agonists may be long-acting, also known as maintenance medicines, or short-acting, also known as rescue medicines. Long-acting maintenance medicines are taken on a regular basis every day. They do not treat sudden symptoms.
 Short-acting rescue medicines start working within minutes. They are taken for sudden symptoms. (D)

There is a degradation of elastic fibers and other components of the extracellular matrix including proteases that are now believed to be patho-physiologically relevant to COPD pathogenesis. Proteases function to facilitate antigen presentation, an inactive host-defensive surfactant protein A. This surfactant protein A stimulates serous and mucous secretions, liberate chemotaxins from the extracellular matrix, inhibit removal of apoptotic cells, induce and inactivate interleukin 8, and activate tumor necrosis factor and interleukin 1 beta.(C)
Rational therapeutic agents may possibly be developed by clarification of which alpha protease actions are of importance in COPD, identification of which of the many proteases elaborated by inflammatory and lung septal (endothelial, epithelial, smooth muscle, and fibroblast) cells perform those actions, and design of small molecules with an appropriate spectrum of protease inhibitory activity. (C)

Management:
Quit smoking Smoking and COPD have long been linked. It is very important for individuals who smoke it quit so that in the future, the rate of decline in lung function can slow down. Although there is no cure for COPD once diagnosed, there are things that can be done to help manage the symptoms. These managing skills include:

Practice breathing is one of many coping mechanisms that help individuals with COPD. Breathing exercises can also be an important part of your COPD treatment plan and may include diaphragmatic breathing, pursed-lip breathing, or controlled coughing. Stay active through exercise which may help improve overall strength and endurance, and may even strengthen the muscles that are used to breathe. It is also important to keep things simple and give oneself more time to accomplish everyday activities. There is no need to become overwhelmed with all tasks all at once. Eating a healthy diet will give any individual the energy needed to accomplish these. If overweight, an individual can plan to lose weight so that their ability to perform daily chores and tasks become easier as well as make it easier to breathe.(D)

Because of COPD alone there are 100,000 deaths per year and increasing. According to WHO, it is the 4th leading cause of death in America and is expected to rise to the 3rd position by 2020. Cigarette smoking is the number one cause of COPD and 25% of Americans smoke. (C)
 
 Causes of COPD:

Long-term smokers are usually the individuals who develop COPD. They are usually associated with a progressive decline in pulmonary function, more rapid than that associated with normal aging. A variety of damaging stimuli such as cigarette smoke, pancreatic elastase, bacterial lipopolysaccharides, cadmium, chloramine-T, oxidants, silica, and severe starvation, can induce changes in animal lungs. (C)

A long term exposure to other lung toxins, chemicals, or irritants such as air pollution or chemical fumes also contribute to COPD. This respiratory disease makes airflow into and out of your lungs difficult therefore reducing your lung function. COPD includes chronic bronchitis, emphysema, or both. (A)
Smoking cigarettes causes oxidant injury. In other words, smoking causes severe oxidative stress on the lungs directly via reactive species in the smoke or indirectly through activation of inflammatory cells. Such oxidative stress on COPD through various biological actions (i.e. cellular injury, oxidation and nitration of proteins, changes in gene expression, stimulation of mucous secretion, inactivation of antiproteases, expression of proinflammatory mediators, remodeling of blood vessels, and enhancement of apoptosis).

Markers of oxidative stress (e.g., hydrogen peroxide, 8-isoprostane, and lipid peroxides) are elevated in the breath or serum of subjects with COPD, and epidemiological studies have demonstrated negative associations of dietary antioxidant intake with pulmonary function and with obstructive airway disease. (C)

Airway inflammation and parenchymal inflammation are consistent findings in COPD. The connection between COPD and airways inflammation is complex. 
  •  First, inflammation is observed in the lungs of smokers who do not meet clinical criteria for diagnosis of COPD. 
  • Second, inflammation persists long after smoking cessation. 
  • Third, there is overlap in the profiles of inflammatory cells and mediators expressed in COPD and in asthma.
  • Fourth, inhaled corticosteroids do not prevent the progressive loss of lung function in subjects with COPD. 
  • Fifth, the increased numbers of infiltrating macrophages, neutrophils, and lymphocytes in the lungs of individuals with COPD are less than those observed in other inflammatory lung conditions that are not associated with the development of COPD.
Characterizing lung inflammation associated with COPD have been compared in studies to the extensive profiling of patients with asthma. Increased numbers of CD8+ T cells in the airways and lung parenchyma of smoking subjects with COPD were witnessed. There was a negative (aka: as one factor increases the other decreases and vice versa) correlation between FEV1 (% predicted) and CD8+ T cell number.

The large airways of smokers with severe COPD show increased numbers of neutrophils, macrophages, and natural killer lymphocytes in comparison with smokers without clinically defined COPD; and each of these cell types is negatively associated with FEV1. Neutrophils tend to localize with the airway epithelium, but nodules of B lymphocytes are found in the submucosa and adventitia. Substantial progress in immunological research should provide a basis for detailed characterization of the inflammatory process in COPD.

Genetic Risk Factors:
A knowledge of genetic determinants of COPD could lead to recognition of biochemical pathways that contribute to the disease and allow targeting of public health interventions to individuals at greatest risk. A program for identification of genes related to COPD should consider several issues: First, simultaneous characterization of multiple phenotypes will be necessary because different genes may be related to different aspects of the disease (e.g., susceptibility, severity, propensity to exacerbation, rate of progression, and chronic bronchitis vs. emphysema). Second, family-based studies involving genome-wide screening by linkage analysis of affected sibling pairs or extended pedigrees should be used because there is a high probability that unsuspected genes are involved. Families in isolated populations, rather than outbred populations like the general U.S.
 population, may be studied more efficiently.

Genetic factors could also contribute to an individual's physical body to be greater predisposed to developing and at a higher risk of progression of COPD. Identification of these genes should be a goal for the near future because pulmonary function is indeed influenced by heredity which is also associated with COPD. 
 
Research:

Advances in lung development and alveolar regeneration have been achieved through various animal studies. These studies were focused on observing alveolar development in the late fetal and postnatal period of the animals' lifespan. Such studies have given much hope in the field of medicine for stimulation of alveolar regeneration because now it is an exciting possibility for developing disease modifying therapies for patients with COPD.

Within this umbrella of animal studies for COPD, research included gene expression and proteomic analysis of the developing lung, how relevant genes that are expressed are regulated, vascularization and lung development and repair, transgenic mice used to evaluate the role of specific growth factors in the lung, and lastly, toxins (such as in utero nicotine) that impair lung growth.

However, it is important to note that in order to determine alveolar regeneration in adults of various species, future studies must focus on the capacity of lungs to mature, capacity for alveolar regrowth, as well as the proper conditions where alveolar regeneration is possible and successful. Research conducted for long-term oxygen therapy, management of sleep disturbance in COPD, alleviation of nocturnal hypoxemia, prevention and treatment of exacerbations, and better tools for disease monitoring should be conducted under controlled circumstances in order for the results to be seen as valid.

More research is needed where COPD is not linked to cigarette neutrophil protease theory. The Neutrophil Protease Theory is the theory that assumes that smoking cigarettes is the only factor that contributes to the causation of COPD. There are far too many unknown and unrelated pathways which cause emphysema and bronchitis. Scientists and researchers alike should aim, through various observations of studies, to conclude a single theory of COPD that encompasses the known pathways/relationships that lead to this chronic disease. (C)

The presence of latent viral infections in the lungs could possibly be another risk factor that leads to COPD. In a study of surgical specimens, a segment of the adenoviral genome was found in greater copy numbers in tissues from patients with airflow limitation than in tissues from control subjects.(C)

In a guinea pig model, latent adenoviral infection potentiated the inflammatory effects of cigarette smoke, and transfection of cells in vitro with adenoviral DNA was shown to activate nuclear factor B and potentiate corticosteroid-resistant production of interleukin 8(C).

The reason as to why animal models are used so often is because they can identify genes that are candidates for pathophysiology ramifications of a specific genotype. Case-control association studies of particular candidate genes will eventually be needed to test the relevance of results obtained in particular families to the disease in the general population. Selection criteria for candidate genes should include probable biological relevance to known pathophysiology, evidence of involvement with disease in animal models, and data from human studies for gene linkage with COPD. Although clinical trials that involve large numbers of well characterized subjects with COPD is not a great or perfect way to attain valid and conclusive results when conducting genetic studies.By the end of the study an archive of the DNA samples of the subjects taking part should have been recorded and kept for later analysis.(C)


Mouse models with inducible, lung-specific expression of particular cytokines have been shown to manifest lung abnormalities that are clearly not attributable to aberrant development of the lung. Overexpression of interleukin 11 in adult mice produced peribronchiolar lymphoid nodules similar to those observed in human COPD but did not cause emphysema. Overexpression in adult mice of either interferon, a major product of CD8+ lymphocytes, or interleukin 13, a mediator associated with CD4+ T cells and asthma, produced emphysema-like changes.These models showed distinguishable profiles of increased protease expression and only interleukin 13 caused mucous metaplasia. A gene-targeting approach (loss of function) has proven useful for testing the contributions of various matrix metallo-proteinases in the development of cigarette smoke-induced emphysema in the mouse. (C)
Links:
(A) http://www.anoro.com/copd.html?rotation=71700000009793970&banner=58700000435532905&kw=6301905368&cc=38533e7470ad&pid=6301905368&google=e_
(B) http://www.theguardian.com/society/2014/feb/13/symptoms-lung-disease-overlooked-study
(C) http://www.nhlbi.nih.gov/health-pro/resources/lung/chronic-obstructive-pulmonary-disease-future-research/workshop-summary
(D)http://www.brovana.com/copd.html?utm_content=BRO_BROSEMCOPD_2_12_16_V1&utm_medium=cpc&utm_source=google&utm_campaign=Brovana_DTC_SEM_Google_FY16_NB_COPD_Exact&utm_term=what_is_copd
*Please note! These images are not mine. They were found on various tumblr sites! If any are yours please let me know so that I can give you credit for them! Also the people in the images have no relation to the diseases, illnesses, or cancers I write about. Thanks so much & enjoy~

41 comments:

  1. (MUST READ: HOW I GOT CURED FROM COPD)
    I am Lydia, I was diagnosed of Chronic obstructive pulmonary disease (COPD) in 2014, the doctor told me it has no permanent cure i was given medications to slow down its progress, i constantly felt my health was deteriorating as i constantly go out of breath especially when i walk or talk for long, this continued till a friend told me about how her mother got cured of COPD through herbs she bought from a South African herbal doctor Dr Ejiro, I contacted this herbal doctor via his email and he sent me the herbal medicine through courier service, when i received the herbal medicine i used it for 3 weeks as prescribed and was totally cured of COPD. Contact this herbal doctor via his email ejiroherbalcure@gmail.com or call +27617403481

    ReplyDelete
    Replies
    1. thank to doctor Emmanuel,I am from USA, I was diagnosed of Emphysema
      (COPD) in 2015 and I have tried all possible means to get cured, i even
      visited phonologist but all to no avail, until i saw a post in a health
      forum about a herbal doctor from Africa who prepare herbal medicine to cure
      all kind of diseases including Emphysema, at first i doubted if it was real
      but decided to give it a try, when i contacted this herbal doctor via his
      email he sent me the Emphysema herbal medicine through courier service,
      when i received this herbal medicine, he gave me step by instructions on
      how to apply it, when i applied it as instructed i was totally cured of
      this deadly disease within 12-14 days of usage, if you are suffering of
      this diseases you can as well Contact this great herbal doctor via his
      email traditionalherbalhealingcentre@gmail.com > or call/whatsapp him at +2348110857969.......

      Delete
    2. After having a persistent cough for over a year, I was diagnosed with COPD
      in March 2015. In 2016 my COPD got worse to the point where not only do I
      have trouble sleeping at night, I also struggle to get air into my lungs. I
      read in a health forum of a herbal centre (native health clinic) who have successful treatment to COPD/Emphysema, i immediately
      contacted the herbal centre via their website and purchased the COPD herbal
      remedy, I used the remedy for 2 weeks, all my symptoms were reversed, i did
      another test for confirmation, i was declared COPD free. email (
      nativehealthclinic@gmail.com) or WhatsApp/Call him on +2348140073965

      Delete
  2. Emphysema Treatment ought to include, obviously, eliminating exposure to emphysema-bringing about poisons. This includes more than the evasion of tobacco smoke. You ought to look at your everyday life and check for different wellsprings of poisons.

    ReplyDelete
  3. Hello Its James Stood, I have never met a great Man, Doctor, Healer like Dr. Ayes, he is a trust worthy man full of respect and compassions, he has done a great thing for me which no one else in this life has never done, I contacted him few weeks ago concerning cure to COPD and to my own greatest surprise he was able to heal me within two weeks of knowing him and not only me has testify the wonderful works of him, my friend also confirmed the herbal medicine sent by Dr Ayes has saved so many lifes here in USA, I don't have much to say here because I have to returned to work, but I must compesate him for his marvelous work which he has done for me and he is really Good and Kind hearted man contact him today and also try him out in getting cure from COPD and you will see what really I am saying is right and he will get you cure by his powerful use of herbs as herbal medicine for you..
    Contact his email address unstopableshrine@gmail.com and unstopableshrine@outlook.com and his website http://unstopableshrine.webs.com
    Thanks and Remain Bless

    ReplyDelete
  4. I was diagnosed of COPD in July 2014. I was on Albuterol Nebs and levalbuterol to ease the situation as i constantly go out of breath when talking or when walking, I was adviced for Lung Volume reduction surgery (LVRS) because my both upper lobes of the lungs were affected, i was making preparation for this surgery when a friend of mine told me about a traditional herbal doctor called doctor Abumere who prepares herbal medicine to cure all kind of diseases including COPD disease, When i contacted Dr Abumere his email and bought the herbal medicine I received the herbal medicine through courier service in 3days, when i received this herbal medicine i used it as prescribed and was totally cured of COPD within 18-20 days of usage, contact Dr Abumere via his email: abumereherbalcentre@gmail.com.

    ReplyDelete
  5. I am from USA, I was diagnosed of Emphysema (COPD) in 2015 and I have tried all possible means to get cured, i even visited pulmonologist but all to no avail, until i saw a post in a health forum about a herbal doctor from south Africa who prepare herbal medicine to cure all kind of diseases including Emphysema, at first i doubted if it was real but decided to give it a try, when i contacted this herbal doctor via his email he sent me the Emphysema herbal medicine through courier service, when i received this herbal medicine, he gave me step by instructions on how to apply it, when i applied it as instructed i was totally cured of this deadly disease within 12-14 days of usage, if you are suffering of this diseases you can as well Contact this great herbal doctor via his email abumereherbalcentre@gmail.com.

    ReplyDelete
  6. OMG!! This is certainly a shocking and a genuine Testimony..I visited a forum here on the internet on the 20TH OF July 2016, And I saw a marvelous testimony of this powerful and great Herbal doctor called DR Lusanda on the forum..I never believed it, because I never heard nor learnt anything about Herbals before.. Not a soul would have been able to influence me about herbal medicines, not until DR Lusanda did it for me and cured me from COPD of 8 years within 3 weeks just as I have read on the internet..I was truly astonished and shocked when my doctor said it was no longer there. I am really short of expressions, and I don't know how much to convey my appreciation to you DR Lusanda, you are a God sent to me and my entire family.. Here is his website: www.drlusandaherbals.weebly.com His Email: drlusandaherbal@gmail.com

    ReplyDelete

  7. I’m here to testify about the great work perfecthealthherbalmedcinehome,run by Dr sithuu . I have been suffering from COPD,and my mother diagnosed with herpes disease for the past 5 years,I had faith in God that me and my mother would be cured someday.me and my mother have been taking treatment from my doctor spending a lot of money just to stay alive , few weeks ago i came across a testimony of one lady on the internet testifying about a herbal home called perfecthealthherbalmedicinehome,run by dr sithuu, on how he cured her from Parkinson virus. And she also gave the email address of the herbal home and advise anybody to contact for help for any kind of diseases , so I emailed them,they replied and told me not to worry that me and my mom will be cured!! Well i never believed it,,but i was so desperate,so i purchased the herbal medicine, well after used as prescribed, few weeks later i started experiencing changes,after 30days i went to my doctor to confirmed if am finally cured behold it was TRUE,me and my mother was totally cured , So friends my advise is if you have such disease or any other at all you can contact them via email: perfecthealthherbalmedicine@gmail.com or website www.perfecthealthherbal.weebly.com

    ReplyDelete
  8. I was diagonose of Emphysema in 2010 and Chronic Obstructive Pulmonary Disease (COPD) 3 years ago, our family doctor told me there was no cure but it can only be controled. Ever since then i have been running heather scepter looking for a solution to my problem because i was going to lose my Job if i dont get better, until i ran into this online testimony of Dr Lusanda who have been curing people of COPD with his herbal remedy i immediately contacted him via their email, to God be thy glory i bought this COPD herbal remedy and was cured within 3 weeks of usage, at last this is a break through for all COPD/emphysema patients contact this herbal clinic via their email drlusandaherbal@drlusandaherbal.com or website on www.drlusandaherbal.com

    ReplyDelete

  9. 2015 my mother was diagnosed of COPD/Emphysema ,i spent a lot of money on her medication till a point i even lost hope,because my mother was gradually dying and lost her memory too, i was so desperate to get my mother back to normal ,so one day my uncle who lives in United Kingdom told me about Dr Lusanda,who helped him get rid of Emphysema with herbal medicine ,i was so shocked when he told me that,but know is true because my uncle cant lie me ,so i contacted Dr Lusanda via his email;drlusandaherbal@gmail.com he replied and ask me to send my home address and my mother's detail and then i purchased the herbal medicine,sent me the herbal medicine through courier service, when i received this herbal medicine used it for 4 weeks, and after 4 weeks of usage my mother was totally cured of COPD/Emphysema,now my mother is living free and happy again ..all thanks to doctor Lusanda ...

    ReplyDelete
  10. Hello,everyone i really find this piece of information very useful to the general public especially those suffering from Acne Pimples and other deadly disease. I was diagnosed of Acne Pimples 3years ago after the demise of my husband before i came across a very good friend from Africa who introduced me to a powerful Herbal Traditionalist called Dr. Osas, of which i contacted and helped in fighting the virus in less than a month. Today am totally free from the disease.All thanks to God and Dr.Osas for his Medicine. CONTACT HIM VIA drosasherbalhome@gmail.com for easy communication you can contact him via WhatSapp +234903542812. He can also cure the following problems 1. EMPHYSEMA 2.HERPES SIMPLEX VIRUS 3. CANCER EX-BACK, 4. PENIS ENGAGEMENT 5. PREGNANCY 6. LUPUS VIRUS 7. ACNE PIMPES contact him via his email drosasherbalhome@gmail.com

    ReplyDelete
  11. Parkinson disease has been ongoing in my family for long..I lost both parents to Parkinson and it is so much pain have not been able to get over. As we all know medically,there is no solution or cure for Parkinson disease and the cost for Medication is very expensive..Someone introduced me to a herbal Clinic(Native Medical Practitioner)in S.A.. i have spent thousands of dollars on medication..I said i will like to try them cos someone introduced me to them..they asked me sorts of questions and i answered back correctly..To cut the story short,they gave me some medicinal herbs and instructed me on how to apply theml..At first i was skeptical but i just gave it a try..I was on this herbal Medication for 4 weeks and i used the herbs according to the prescription..i decided to visit my doctor for another test..Honestly speaking, i never believe all he was saying until after the test when my doctor mention the statement that am Parkinson disease negative and my doctor was shocked as well....If you are out there suffering from this deadly disease you can also contact them via email: Healthherbalclinic@gmail.com or website on www.Healthherbalclinic.weebly.com

    ReplyDelete
  12. Am Success Puga from USA. I can’t believe this. A great testimony that i must share to all HERPES patient in the world i never believed that their could be any complete cure for HERPES or any cure for HERPES,i saw people’s testimony on blog sites of how DR Ekpiku prepare herbal cure and brought them back to life again. i had to try it too and you can,t believe that in just few weeks i started using it all my pains stop gradually and i had to leave without the HERPES DRUGS the doctor gave to me. Right now i can tell you that few months now i have not had any pain,delay in treatment leads to death. Here is his email:ekpikuspellhomeofgrace@hotmail.com or ekpikuspellhomeofgrace@gmail.com his WHATSAPP number is +2348073673757
    DOCTOR Ekpiku CAN AS WELL CURE THE FOLLOWING DISEASE:-

    1. HIV/AIDS
    2. HERPES
    3. CANCER
    4. ALS
    5. Hepatitis B
    6. Parkinson

    ReplyDelete
  13. thank to doctor Emmanuel,I am from USA, I was diagnosed of Emphysema
    (COPD) in 2015 and I have tried all possible means to get cured, i even
    visited phonologist but all to no avail, until i saw a post in a health
    forum about a herbal doctor from Africa who prepare herbal medicine to cure
    all kind of diseases including Emphysema, at first i doubted if it was real
    but decided to give it a try, when i contacted this herbal doctor via his
    email he sent me the Emphysema herbal medicine through courier service,
    when i received this herbal medicine, he gave me step by instructions on
    how to apply it, when i applied it as instructed i was totally cured of
    this deadly disease within 12-14 days of usage, if you are suffering of
    this diseases you can as well Contact this great herbal doctor via his
    email traditionalherbalhealingcentre@gmail.com > or call/whatsapp him at +2348110857969.......

    ReplyDelete
  14. I was diagnosed of Emphysema (copd)9 months ago which affected my breathing badly, my doctor advice me for Lungs Volume reduction surgery (LVRS) because my both upper lobes of the lungs were involved, i was making preparation for this when a friend of mine told me about a herbal doctor from Africa, doctor Avens who prepares herbal medicine to cure all kind of diseases including Emphysema, i contacted Dr Avens via his email and he sent me Emphysema herbal medicine via courier service, when i received this herbal medicine i applied it as instructed and was totally cured of Emphysema within 15 days of usage, i never had to go for the surgery again as i was totally free from emphysema, all thanks to Dr Avens, contact Dr Avens via his email doctoravens@outlook.com or whatsapp+2349077873085

    ReplyDelete
  15. I smoked for 20 years, October 2014 i was diagnosed of Emphysema I may have had it for 6 months to 1 year prior to diagnosis. It started with a dry cough, shortness of breath, and fatigue. A chest x-ray confirmed it and I was placed on corticosteroids. my doctor told me there is no permanent cure for the disease, i was given bronchodilators to help me relax my bronchiolar muscles, I managed on with the disease till a friend told me about a herbal clinic from johannesburg who sell herbal medicines to cure all kind of lung related diseases including emphysema, I spoke to few people who used the treatment here in USA and they all gave positive responses I contacted this herbal clinic via there email and made purchase of the emphysema herbal medicine, i received the herbal medicine through DHL within 5 days, when i received the herbal medicine i applied it as prescribed and was totally cured of emphysema within 7 weeks of usage, the symptoms reduced till i even forgot i had emphysema, i went back to my doctor for diagnosis with spirometry and he confirmed i was free from the disease, contact this herbal clinic via there email healthherbalclinic @ gmail . com or website on www . healthherbalclinic . weebly . com

    ReplyDelete
  16. WE WELCOME YOU ALL TO DEVANSH HERBAL HEALTH CARE.
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    ReplyDelete
  17. I am 50 years old and I was told I had COPD 10 years ago. I immediately quit smoking, but as the years pass by my situation gets worse, and I started having attacks once a year, then every six months, and later every 3 to 4 months I was in the hospital. I used to be able to exercise, but it was so hard because i was out of breath. I see people say exercise, but understand this, you can`t exercise if you`re out of breath. I live off steroids and became type 2 diabetic from the steroids, but they`were the only medicine that kept me going. No one knows how you really feel unless they have been through your situation, not even some doctors. When the steroids no longer helps, i was introduced to Health herbal clinic in Johannesburg who have successful herbal treatment to COPD and other lungs diseases. I spoke to few people who used the treatment here in USA and they all gave a positive response, so i immediately purchased the copd herbal remedy and commenced usage, i used the herbal supplement for only 9 weeks, all symptoms gradually faded away, herbs are truly gift from God. contact this herbal clinic via their email healthherbalclinic @ gmail. com or visit www. healthherbalclinic. weebly. com

    ReplyDelete
  18. I want to use this medium to appreciate the admin of this page for allowing me to share my story.I believe that this will help others going through what i went through over the years to find a cure like i did. i was diagonosed of COPD which i suffered for so many years, despite the different english medications i took in order to find a cure, it didn't work. i started having complications resulting from those english medications i was taking over the years. as a result of these complications from my drugs, i went in search for a natural cure where i saw a testimony of someone who suffered the same sickness i was going through and the person got his cure through herbal medication, then, i followed the email he shared and i contacted the doctor, i got my cure as well, incase you are going through same sickness, you may contact the doctor for more information through his email: drallenchase@gmail.com

    ReplyDelete
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    emphysema treatment

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  21. My husband was diagnosed several years ago with emphysema. He was able to quit smoking and we stayed on top of any illness. He has been hospitalized with pneumonia every year. His breathing has been getting worse but oxygen levels stay in the 97 to 98 range except when he's in hospital. For a year now he has been passing out. It is only for 1 to 3 minutes and was only when he would start coughing. The doctor changed his medications around but he passes out when breathing a bit hard. Also his feet swell up and are numb all the time. He then started using a cane. i searched for alternative treatment before i was introduced to Health herbal clinic by a friend here in the United states she told me they have successful herbal treatment to Emphysema and other lungs diseases. I spoke to few people who used the treatment here in USA and they all gave a positive response, so i immediately purchased the Emphysema herbal formula for my husband and he commenced usage, its totally unexplainable how all the symptoms totally dissapeared, his cough was gone and he no longer experience shortness of breath(dyspnea), contact this herbal clinic via their email healthherbalclinic@ gmail. com Or website www .healthherbalclinic. weebly. com. Herbs are truely gift from God

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  22. The last thing I will ever do is to believe on MEDICAL drugs intense of COPD , I am Anne Chris, New Zealand. I want to appreciate the great work of Dr Abumere, I have been diagnose of COPD for a period of 3years,I’ve lose all hope that there is no cure and I have been taken medicine to sustain myself till I got to know about Dr Abumere through a friend who cured of Chronic obstructive pulmonary . I contacted them by via email>abumereherbalcentre@gmail.com and Medicine sent to me, which I took as prescribed for some period of days and I went to the hospital after consuming the medicine and I was confirmed Negative after 3 years of being positive, it is indeed a miracle honestly,you can contact their email or visit their website on www.abumereherbalcentre.simplesite.com

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  23. ALL THANKS TO DR WILLIAMS FOR THE GREAT DEED HE HAVE DON FOR MY FAMILY.This information will be useful for Epilepsy and stroke patients who is willing to use herbal medicine. My daughter had temporal lobe epilepsy, She had seizure and had a grand mal with rage episode. Our daughter's seizure is constant throughout the day. We had used several medicine which include: Epilim and Keppra, experience seizure control at the cost of serious debilitating side effects. It was during a casual conversation with a friend that I learned about herbal Dr. William on how he help her cure his son from stroke and so many others with different illness,his medicine does not have any side effect.after my daughter have finish taking dr williams medicine I am glad to say that he has been seizure-free since July 2015 after taking William medicine. this a miracle cure?contact him for more detail (drwilliams098765@gmail.com)

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    1. Am Gorege vanisa by name, i was diagnosed with Herpes for 7 years i lived in pain with the knowledge that i wasn’t going to ever be well again i contacted so many herbal doctors on this issue and wasted a large sum of money but my condition never got better i was determined to get my life back so one day i saw mr josha post on how Dr abaka saved him from the VIRUS with his herbal medicine i contacted Dr abaka on his email address drabakaspelltemple@gmail.com we spoke on the issue i told him all that i went through and he told me not to worry that everything will be fine again so he prepared the medicine and send it to me through courier service and told me how to use it,after 14 days of usage I went to see the doctor for test ,then the result was negative,am the happiest man on earth now. this testimony is real.thanks to Dr abaka God bless you. you can also reach him on his number +2349063230051.

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  24. I was not really having a problem breathing at first. My throat was burning; I thought I had strep throat. I had pain in my neck, and there was swelling around my collar bone. The first doctor I went to said he did not know why there was swelling. He gave me antibiotics and told me that if the swelling was not better to come back in two weeks. I went back in two weeks and he said he did not know what was wrong. Since I do not have insurance, I went to a hospital emergency room, and they said I have COPD.The disease does not improve. My "good days" are far and few these days. My dad and his dad died from this. I am only writing this to inform others that nothing was really working to help my condition.I started on COPD herbal formula i ordered from Health Herbal Clinic,i read reviews from other previous patients who used the herbal formula, my symptoms totally declined over a 5 weeks use of the COPD natural herbal formula. i am now doing very well, my lungs are totally repaired!! Visit there website www. healthherbalclinic. net

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  25. Natural Treatment for Emphysema  can help to support your lungs and often work well with a conventional treatment plan. There are a number of natural treatments that can help, including hypnosis.

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  26. Thyme is a useful natural herbs for the  Emphysema Natural Treatment . Thyme ensures as well as invigorates and reinforces the nerves. In addition, it mitigates physical and additionally mental depletion. It helps the immune system. 

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  27. Grape seed and green tea are included in the Emphysema Herbal Treatment as they provide antioxidant support and have various general health enhancing properties.

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  28. I got diagnosed with hpv, i have be dealing with this mess for the past 7yrs. On till i got review online about natural cure people testifies how they got cured with natural treatment. And i order the treatment, after taking it for two weeks i totally got cured with herbal treatment. I'm recommending you diagnosis with hpv should get this treatment via; dronokunherbalcure@gmail.com or whatsapp call.. +2349064844957

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  29. Hiv disease for the last 3 years and had pain hard to eat and cough are nightmares,especially the first year At this stage, the immune system is severely weakened, and the risk of contracting opportunistic infections is much greater. However, not everyone with HIV will go on to develop AIDS. The earlier you receive treatment, the better your outcome will be.I started taking ARV to avoid early death but I had faith in God that i would be healed someday.As a Hiv patent we are advise to be taking antiretroviral treatments to reduce our chance of transmitting the virus to others , few weeks ago i came on search on the internet if i could get any information on Hiv treatment with herbal medicine, on my search i saw a testimony of someone who has been healed from Hiv her name was Achima Abelard and other Herpes Virus patent Tasha Moore also giving testimony about this same man,Called Dr Itua Herbal Center.I was moved by the testimony and i contacted him by his Email.drituaherbalcenter@gmail.com We chatted and he send me a bottle of herbal medicine I drank it as he instructed me to.After drinking it he ask me to go for a test that how i ended my suffering life of Hiv patent,I'm cured and free of Arv Pills.I'm forever grateful to him Drituaherbalcenter.Here his contact Number +2348149277967...He assure me he can cure the following disease..Hiv,Cancer,Herpes Virus,Lyme Disease,Epilepsy, ,Bladder Cancer,Colorectal Cancer,Breast Cancer,Kidney Cancer,Leukemia,Lung Cancer,Non Hodgkin Lymphoma,Skin Cancer,Lupus,Uterine Cancer,Prostate Cancer, fibromyalgia ,ALS,Hepatitis,Copd,Parkinson disease.Genetic disease,Fibrodysplasia disease,Fibrodysplasia Ossificans Progressiva,Fluoroquinolone Toxicity Syndrome,Liver/Kidney Inflammatory,Men/Woman infertility, bowel disease ,Huntington's disease ,Diabetes,Fibroid...

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  30. I had COPD for 9 years. My first symptoms were dry cough, chest tightness and shortness of breath. My first chest x-ray only showed bronchitis. Finally I went to a pulmonologist and was diagnosed with COPD.i have used all the medication yet they don’t work, last year December I was told by a formal emphysema patient to use  totalcureherbsfoundation. com herbal treatment which I really did,i was surprise the herbal products effectively get rid of my COPD totally. When you get where you cannot breathe it may be too late. Good luck to each and every one that will be trying their herbal treatment .

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  31. I was diagnose with human papilloma virus (HPV) 4 years ago and i met a doctor he told me there is no cure and i have be taking some medication the warts multiplied when trying to removed them and it got me embarrass and pains, luckily few weeks ago i was recommend to Dr Onokun for natural treatment after one week i got 100% cure and all the wart and pains got disappeared, i sheared this post because its part of my life experience, encase anyone need speedy help about this cure email Dr Onokun via,
    dronokunherbalcure@gmail.com

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  32. I thank Allah for bringing Dr Bayo Ewebe into my life, I diagnosed with COPD doctors said no cure just treatment treatment not good enough I find help online I see Dr Bayo Ewebe he make herbal medicine for me now COPD no more. Herbal medicine best medicine if you have contact Dr.bayoherbalkingdom @ yahoo. com sickness will go inshallah

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  33. I'm 59 years old and female. I was diagnosed a couple of months ago with COPD and I was beyond scared! My lung function test indicated 49% capacity. After having had flu a year ago, the shortness of breath, coughing and chest pains continued even after being treated with antibiotics. I've been smoking two packs a day for 36 years. Being born without a sternum caused my ribs to be curled in just one inch away from my spine, resulting to underdeveloped lungs. At age 34 I had surgery and it was fixed. Unfortunately my smoking just caused more damage to my already under developed lungs. The problem was having is that I enjoy smoking and don't want to give up! Have tried twice before and nearly went crazy and don't want to go through that again. I saw the fear in my husband and children's eyes when I told them about my condition then they start to find solution on their own to help my condition.I am an 59 now with moderately severe COPD emphysema which I know was from my years of smoking. I started smoking as a teen in high school when smoking was socially acceptable. I remember when smoking was permitted in hospitals. It was not known then how dangerous cigarettes were for us, and it seemed everybody smoked, i was able to get rid of my COPD lung condition through the help of total cure herbal foundation my husband bought, totalcureherbsfoundation .c om has the right herbal formula to help you get rid and repair any lung conditions and cure you totally. I wish anybody who starts smoking at a young age would realize what will eventually happen to their bodies if they continue that vile habit throughout their lives.

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  35. After years of working in construction and smoking cigarettes,I was diagnosed with COPD and pulmonary fibrosis, i started on COPD/IPF Herbal formula treatment from multivitamin herbal cure, the treatment worked incredibly for my lungs condition. I used the herbal treatment for over 7 weeks, it reversed my chronic obstructive pulmonary disease. My severe shortness of breath, dry cough, low energy, fatigue, chest tightness and others gradually disappeared. Visit multivitamin herbal cure official web page multivitamincare . org This COPD and pulmonary fibrosis treatment has improved the quality of my life greatly, i breath much better and It feels comfortable!

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  36. i started on COPD Herbal treatment from Ultimate Health Home, the treatment worked incredibly for my lungs condition. I used the herbal treatment for almost 4 months, it reversed my COPD. My severe shortness of breath, dry cough, chest tightness gradually disappeared. Reach Ultimate Health Home via their website www.ultimatelifeclinic.com I can breath much better and It feels comfortable!

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    1. Hey! I am matina from UK. My husband battled with COPD for years but I am glad right now that his condition swiftly changed positively as my husband can now breathe normal as every other person after undergoing COPD herbal  remedies from This Same ULTIMATE LIFE CLINIC

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  37. Rhonda S.’s COPD made her feel short of breath and like she was constantly dragging. While her inhalers helped some, she just didn’t feel like herself anymore.
    After having life-threatening pneumonia, she knew something had to change. A friend of hers mentioned multivitamin herbal formula restoration treatment, so Rhonda did
    some research and decided to receive treatment at the multivitamin herbal cure. “I started to feel better almost right away,” Rhonda said.
    And, along with feeling better, she began to do things she couldn’t do before treatment. Now, Rhonda can take showers, work in her flower garden, and she enjoys having more energy. It’s with a great deal of hope, Rhonda says, “I feel more like myself.”
    Like Rhonda, you can breathe easier and bring normal life back within reach. If you or someone you love has a chronic lung disease and would like more information, contact us today by calling (+1 (956) 758-7882 to visit their website multivitamincare .org

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